Telomere-binding proteins, their interaction partners and transcription factors play a prominent role in telomere maintenance and telomerase activation. We examined mRNA expression levels of tankyrase 1 and 2, TRF1 and 2, c-myc, TERT and TR in Gallus domesticus, the domestic chicken, by quantitative real-time PCR, establishing expression profiles for three contrasting cell systems: the pluripotent gastrula, differentiated embryo fibroblasts and transformed DT40 cells.
Swanberg and Delany, Mechanisms of Ageing and Development (2005)
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